• 靶点-Target： TFIIB
• MW(Observed)： 34kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant human TFIIB protein fragments expressed in E.coli.
• 特异性： This antibody detects endogenous levels of TFIIB and does not cross-react with related proteins.
• 基因名称： gtf2b
• Organism-1： Human
• 基因ID-1： 2959
• SwissProt-1： Q00403
• Organism-2： Mouse
• SwissProt-2： P62915
• 背景： general transcription factor IIB(GTF2B) Homo sapiens This gene encodes the general transcription factor IIB， one of the ubiquitous factors required for transcription initiation by RNA polymerase II. The protein localizes to the nucleus where it forms a complex (the DAB complex) with transcription factors IID and IIA. Transcription factor IIB serves as a bridge between IID， the factor which initially recognizes the promoter sequence， and RNA polymerase II. [provided by RefSeq， Jul 2008]，
• 细胞定位： Nucleus . Chromosome . Non-acetylated form colocalizes with DNA in the G0/1， S and G2 phases of the cell cycle， but not during mitosis (PubMed:24441171). Acetylated form colocalizes at transcriptionally silent mitotic chromatids during mitosis at metaphase， anaphase， and telophase phases of the cell cycle (PubMed:24441171). .

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