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- 靶点-Target: PP2A α and β
- MW(Observed): 36kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:2000
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant human full length PP2A beta protein expressed in E.coli
- 特异性: This antibody detects endogenous levels of PP2A alpha and PP2A beta.
- 基因名称: ppp2cb
- Organism-1: Human
- 基因ID-1: 5516
- SwissProt-1: P62714
- Organism-2: Mouse
- SwissProt-2: P62715
- 背景: This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit. [provided by RefSeq, Mar 2010],
- 细胞定位: Cytoplasm . Nucleus . Chromosome, centromere . Cytoplasm, cytoskeleton, spindle pole . In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.