• 靶点-Target： PP5
• MW(Calculated)： 57kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:1000-1:2000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： Affinity purification
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant human PP5 protein fragments expressed in E.coli.
• 特异性： PP5 Monoclonal Antibody detects endogenous levels of PP5 protein.
• 基因名称： PPP5C
• 蛋白名称： Serine/threonine-protein phosphatase 5
• Organism-1： Human
• 基因ID-1： 5536
• SwissProt-1： P53041
• Organism-2： Mouse
• 基因ID-2： 19060
• SwissProt-2： Q60676
• Organism-3： Rat
• 基因ID-3： 65179
• SwissProt-3： P53042
• 背景： This gene encodes a serine/threonine phosphatase which is a member of the protein phosphatase catalytic subunit family. Proteins in this family participate in pathways regulated by reversible phosphorylation at serine and threonine residues; many of these pathways are involved in the regulation of cell growth and differentiation. The product of this gene has been shown to participate in signaling pathways in response to hormones or cellular stress， and elevated levels of this protein may be associated with breast cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq， Feb 2011]，
• 细胞定位： Nucleus . Cytoplasm . Cell membrane . Predominantly nuclear (PubMed:15383005). But also present in the cytoplasm (PubMed:15383005). Translocates from the cytoplasm to the plasma membrane in a RAC1-dependent manner (PubMed:19948726). .

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