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- 靶点-Target: Pirh2
- MW(Calculated): 30kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: Affinity purification
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant fragment of human Pirh2 expressed in E. Coli.
- 特异性: Pirh2 Monoclonal Antibody detects endogenous levels of Pirh2 protein.
- 基因名称: RCHY1
- 蛋白名称: RING finger and CHY zinc finger domain-containing protein 1
- Organism-1: Human
- 基因ID-1: 25898
- SwissProt-1: Q96PM5
- Organism-2: Mouse
- SwissProt-2: Q9CR50
- 背景: The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2013],
- 细胞定位: Nucleus. Nucleus speckle. Cytoplasm.