• 靶点-Target： p40/p63
• MW(Calculated)： 77kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： Affinity purification
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Synthesized peptide of human p63.
• 特异性： p63 Monoclonal Antibody detects endogenous levels of p63 protein.
• 基因名称： TP63
• 蛋白名称： Tumor protein 63
• Organism-1： Human
• 基因ID-1： 8626
• SwissProt-1： Q9H3D4
• Organism-2： Mouse
• 基因ID-2： 22061
• SwissProt-2： O88898
• Organism-3： Rat
• 基因ID-3： 246334
• SwissProt-3： Q9JJP6
• 背景： tumor protein p63(TP63) Homo sapiens This gene encodes a member of the p53 family of transcription factors. The functional domains of p53 family proteins include an N-terminal transactivation domain， a central DNA-binding domain and an oligomerization domain. Alternative splicing of this gene and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties. These isoforms function during skin development and maintenance， adult stem/progenitor cell regulation， heart development and premature aging. Some isoforms have been found to protect the germline by eliminating oocytes or testicular germ cells that have suffered DNA damage. Mutations in this gene are associated with ectodermal dysplasia， and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrim
• 细胞定位： Nucleus .

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