• 靶点-Target： IRAK-4
• MW(Calculated)： 52kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;IHC 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;IF 1:50-200
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： Affinity purification
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant fragment of human IRAK-4 expressed in E. Coli.
• 特异性： IRAK-4 Monoclonal Antibody detects endogenous levels of IRAK-4 protein.
• 基因名称： IRAK4
• 蛋白名称： Interleukin-1 receptor-associated kinase 4
• Organism-1： Human
• 基因ID-1： 51135
• SwissProt-1： Q8TDF7
• 背景： This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq， Aug 2011]，
• 细胞定位： extracellular space，intracellular，nucleus，cytoplasm，cytosol，plasma membrane，endosome membrane，

资料下载