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- 靶点-Target: ACTA2
- MW(Calculated): 42kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: Affinity purification
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Synthesized peptide of human ACTA2.
- 特异性: ACTA2 Monoclonal Antibody detects endogenous levels of ACTA2 protein.
- 基因名称: ACTA2
- 蛋白名称: Actin, aortic smooth muscle
- Organism-1: Human
- 基因ID-1: 59
- SwissProt-1: P62736
- Organism-2: Mouse
- 基因ID-2: 11475
- SwissProt-2: P62737
- Organism-3: Rat
- 基因ID-3: 81633
- SwissProt-3: P62738
- 背景: The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2008],
- 细胞定位: Cytoplasm, cytoskeleton.