• 靶点-Target： MCM2
• MW(Calculated)： 102kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;IHC 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;IF 1:50-200
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： Affinity purification
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant fragment of human BM28 expressed in E. Coli.
• 特异性： BM28 Monoclonal Antibody detects endogenous levels of BM28 protein.
• 基因名称： MCM2
• 蛋白名称： DNA replication licensing factor MCM2
• Organism-1： Human
• 基因ID-1： 4171
• SwissProt-1： P49736
• Organism-2： Mouse
• 基因ID-2： 17216
• SwissProt-2： P97310
• 背景： The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4， 6， and 7， and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated， and thus regulated by， protein kinases CDC2 and CDC7. Multiple alternatively spliced transcript variants have been found， but the full-length nature of some variants has not been defined. [provided by RefSeq， Oct 2012]，
• 细胞定位： Nucleus . Chromosome . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .

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