• 靶点-Target： Tubulin α
• MW(Observed)： 50kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Acetyl
• 推荐稀释比： WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： The antiserum was produced against synthesized Acetyl-peptide derived from human TUBA1B around the Acetylation site of Lys352. AA range:311-360
• 特异性： Acetyl-Tubulin α (K352) Polyclonal Antibody detects endogenous levels of Tubulin α protein only when acetylated at K352.
• 基因名称： TUBA1A/TUBA1B/TUBA1C/TUBA3C/TUBA4A/TUBA8
• 蛋白名称： Tubulin alpha-1A chain/Tubulin alpha-1B chain/Tubulin alpha-1C chain/Tubulin alpha-3C/D chain/Tubulin alpha-4A chain/Tubulin alpha-8 chain
• Organism-1： Human
• 基因ID-1： 7846
• SwissProt-1： Q71U36
• Organism-2： Mouse
• 基因ID-2： 22142
• SwissProt-2： P68369
• Organism-3： Rat
• 基因ID-3： 64158
• SwissProt-3： P68370
• 背景： Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily， which is composed of six distinct families. Genes from the alpha， beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules， while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes， which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q.
• 细胞定位： Cytoplasm， cytoskeleton.

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