• 靶点-Target： E2F-4
• MW(Observed)： 43kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Acetyl
• 推荐稀释比： WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： The antiserum was produced against synthesized Acetyl-peptide derived from human E2F4 around the Acetylation site of Lys96. AA range:61-110
• 特异性： Acetyl-E2F-4 (K96) Polyclonal Antibody detects endogenous levels of E2F-4 protein only when acetylated at K96.
• 基因名称： E2F4
• 蛋白名称： Transcription factor E2F4
• Organism-1： Human
• 基因ID-1： 1874
• SwissProt-1： Q16254
• Organism-2： Mouse
• 基因ID-2： 104394
• SwissProt-2： Q8R0K9
• 背景： The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain， a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP)， a transactivation domain enriched in acidic amino acids， and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB， p107 and p130， but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated ge
• 细胞定位： Nucleus.

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