• 靶点-Target： ATF5
• MW(Observed)： 30kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Acetyl
• 推荐稀释比： WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： The antiserum was produced against synthesized Acetyl-peptide derived from human ATF5 around the Acetylation site of Lys29. AA range:1-50
• 特异性： Acetyl-ATF-5 (K29) Polyclonal Antibody detects endogenous levels of ATF-5 protein only when acetylated at K29.
• 基因名称： ATF5
• 蛋白名称： Cyclic AMP-dependent transcription factor ATF-5
• Organism-1： Human
• 基因ID-1： 22809
• SwissProt-1： Q9Y2D1
• Organism-2： Mouse
• 基因ID-2： 107503
• SwissProt-2： O70191
• Organism-3： Rat
• 基因ID-3： 282840
• SwissProt-3： Q6P788
• 背景： function:Transcriptional activator which binds the cAMP response element (CRE) (consensus: 5‘-GTGACGT[AC][AG]-3‘)， a sequence present in many viral and cellular promoters and blocks the differentiation of neuroprogenitor cells into neurons. Its transcriptional activity is enhanced by CCND3 and slightly inhibited by CDK4.，similarity:Belongs to the bZIP family.，similarity:Contains 1 bZIP domain.，subunit:Binds DNA as a dimer. Interacts with PTP4A1/PRL-1 (By similarity). Interacts with CCND3， but not with CCND1 or CCND2.，
• 细胞定位： Cytoplasm . Nucleus . Cytoplasm， cytoskeleton， microtubule organizing center， centrosome . Actively transported to the centrosome and accumulated in the pericentriolar material (PCM) during G1 to M phase via a microtubule-dependent mechanism. During late telophase and cytokinesis， translocates from the centrosome to the midbody. .

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