• 靶点-Target： Ku70/XRCC6
• MW(Observed)： 70kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Acetyl
• 推荐稀释比： WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： Synthesized acetyl-peptide derived from the human Ku-70 around the acetylation site of K539.
• 特异性： Acetyl-Ku-70 (K539) Polyclonal Antibody detects endogenous levels of Ku-70 protein only when acetylated at K539.
• 基因名称： XRCC6
• 蛋白名称： X-ray repair cross-complementing protein 6
• Organism-1： Human
• 基因ID-1： 2547
• SwissProt-1： P12956
• Organism-2： Mouse
• SwissProt-2： P23475
• 背景： The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair， transposition， and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq， Jul 2008]，
• 细胞定位： Nucleus . Chromosome .

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