• 靶点-Target： Cathepsin G
• MW(Observed)： 28kD，26kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： The antiserum was produced against synthesized peptide derived from human CATG. AA range:2-51
• 特异性： Cleaved-Cathepsin G (I21) Polyclonal Antibody detects endogenous levels of fragment of activated Cathepsin G protein resulting from cleavage adjacent to I21.
• 基因名称： CTSG
• 蛋白名称： Cathepsin G
• Organism-1： Human
• 基因ID-1： 1511
• SwissProt-1： P08311
• Organism-2： Mouse
• 基因ID-2： 13035
• SwissProt-2： P28293
• Organism-3： Rat
• SwissProt-3： P17977
• 背景： The protein encoded by this gene， a member of the peptidase S1 protein family， is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C， and may participate in the killing and digestion of engulfed pathogens， and in connective tissue remodeling at sites of inflammation. In addition， the encoded protein is antimicrobial， with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq， Sep 2014]，
• 细胞定位： Cell membrane ; Peripheral membrane protein . Cytoplasmic granule . Secreted . Cytoplasm， cytosol . Lysosome . Nucleus . Secreted by activated neutrophils (PubMed:3390156). Detected in synovial fluid (PubMed:32144329). Localizes to lysosomes in B cells where it is not endogenously synthesized but is internalized from the cell membrane (PubMed:15100291). Localizes to the nucleus during apoptosis (PubMed:11259672). .

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