• 靶点-Target： Caspase-2
• MW(Observed)： 22kD
• 宿主物种-Host Species： Rabbit
• 同种型-Isotype： IgG
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 浓度： 1 mg/ml
• 克隆性： Polyclonal
• 免疫原： The antiserum was produced against synthesized peptide derived from human Caspase 2 p18 C-ternal. AA range:276-325
• 特异性： Cleaved-Caspase-2 p18 (T325) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-2 p18 protein resulting from cleavage adjacent to T325.
• 基因名称： CASP2
• 蛋白名称： Caspase2
• Organism-1： Human
• 基因ID-1： 835
• SwissProt-1： P42575
• Organism-2： Mouse
• 基因ID-2： 12366
• SwissProt-2： P29594
• Organism-3： Rat
• 基因ID-3： 64314
• SwissProt-3： P55215
• 背景： This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways， cell cycle maintenance， and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease， Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq， Jan 2011]，
• 细胞定位： nucleus，cytoplasm，mitochondrion，cytosol，membrane，

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