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HepG2细胞(人肝癌细胞)
HepG2细胞(人肝癌细胞)
  • 商品货号:CL0137
  • 活动价: ¥998元
    市场价:¥1138元
    已售 45 件 | 评价 0 人次 | 关注度 11035
    • 细胞信息
     
    发货规格 1×10⁶
    别名 HEP-G2; Hep G2; HEP G2; HepG2; HEPG2
    形态 上皮细胞样
    生长特性 贴壁
    培养条件 DMEM+10%FBS+1%P/S
    冻存条件 90%FBS+10%DMSO
    传代方式 胰酶消化
    倍增时间 50~60h
    传代比例 1:2~1:4
    换液频率 每周2~3次
    • 细胞背景
     
    种属 人源
    组织来源 肝脏
    肿瘤类型 肝癌
    供体信息 15岁白人男性
    背景描述 HepG2细胞是一种肝母细胞瘤细胞系,是生物科学的基石,特别是在肝癌研究中。 人肝细胞系(如HepG2)通常用作原代人肝细胞的体外模型。这些细胞系具有无限增殖、稳定的表型、易于获取和易于操作等优点。然而,与原代肝细胞相比,它们表现出某些代谢功能的表达降低。
    • 遗传背景
     
    蛋白表达 p53 positive,Albumin, alpha-fetoprotein (alpha fetoprotein), alpha1 acid glycoprotein (alpha-1 acid glycoprotein), alpha1 antitrypsin (alpha-1-antitrypsin), alpha1 antichymotrypsin, (alpha-1-antichymotrypsin), alpha2 HS glycoprotein (alpha-2-HS- glycoprotein), alpha2 macroglobulin (alpha-2-macroglobulin), beta lipoprotein (beta-lipoprotein), ceruloplasmin, C4 and C3 activator, fibrinogen, haptoglobin, plasminogen, retinol binding protein (retinolbinding protein), transferrin
    同工酶 insulin, insulin-like growth factor II (IGF II)
    抗原表达 no, in immunosuppressed mice,Yes, in semisolid medium

    参考文献

    A near-infrared ratiometric fluorescent probe for simultaneous detection of hydrazine and hypochlorous acid in biological systems and its portable detection in …(2025-05-05)
    IF: 11.30
    作者:Yueyin Liang ,Tongtong Xu ,Xiaoya Yue ,Song Xu ,Xu Xu ,Shifa Wang ,Zhonglong Wang
    单位:南京林业大学
    期刊: Journal of Hazardous Materials
    DOI: 10.1016/j.jhazmat.2025.137425
    Theabrownin from dark tea ameliorates insulin resistance via attenuating oxidative stress and modulating IRS-1/PI3K/Akt pathway in HepG2 cells(2023-09-05)
    IF: 4.80
    作者:Jia Liu Xuan Wang Yuanqin Zhu Huilin Deng Xin Huang Pallavi Jayavanth Ying Xiao Jianlin Wu Rui Jiao
    单位:暨南大学
    期刊: Nutrients
    DOI: 10.3390/nu15183862
    Comprehensive analysis of antibacterial and anti-hepatoma activity of metabolites from jujube fruit(2022-06-01)
    IF: 4.80
    作者:Qianqian Shi, Xi Li, Dajun Zhu, Junjun Jiang, Xingang Li
    单位:西北农林科技大学
    期刊: Food Bioscience
    DOI: 10.1016/j.fbio.2021.101511
    Rab11-FIP4 interacts with ARF5 to promote cancer stemness in hepatocellular carcinoma(2023-07-17)
    IF: 4.30
    作者:Feifeng Song, Qi Zhang, Xixuan Lu, Tong Xu, Qing Hu, Xiaoping Hu, Weijiao Fan, Yiwen Zhang & Ping Huang
    单位:杭州医学院附属浙江省人民医院
    期刊: Journal of Physiology and Biochemistry
    DOI: 10.1007/s13105-023-00972-2
    Identification of Cuproptosis-Related Patterns Predict Prognosis and Immunotherapy Response in Hepatocellular Carcinoma(2024-12-11)
    IF: 4.20
    作者:Kai Guo, Tianbing Wang, Jimin Yin, Shoushan Yang, Haodong Cui, Zichuan Cao, Qiang Zhao, Gongbo Xie, Jian Lu, Guosheng Gu, Wenyong Wu
    单位:合肥市第二人民医院
    期刊: Journal of Cellular and Molecular Medicine
    DOI: 10.1111/jcmm.70224
    Exploring the underlying mechanisms of fisetin in the treatment of hepatic insulin resistance via network pharmacology and in vitro validation(2023-11-23)
    IF: 3.90
    作者:Tian Li, Junjun Ling, Xingrong Du, Siyu Zhang, Yan Yang and Liang Zhang
    单位:西南医科大学
    期刊: Nutrition & Metabolism
    DOI: 10.1186/s12986-023-00770-z
    Direct separation and enumeration of CTCs in viscous blood based on co-flow microchannel with tunable shear rate: a proof-of-principle study(2022-09-01)
    IF: 3.80
    作者:Mengnan Li, Chuang Ge, Yuping Yang, Minshan Gan, Yi Xu, Li Chen & Shunbo Li
    单位:重庆大学
    期刊: Analytical and Bioanalytical Chemistry
    DOI: 10.1007/s00216-022-04299-7
    Single-cell transcriptome analysis reveals the metabolic changes and the prognostic value of malignant hepatocyte subpopulations and predict new therapeutic …(2023-01-31)
    IF: 3.50
    作者:Cuifang Han Jiaru Chen Jing Huang Riting Zhu Jincheng Zeng Hongbing Yu Zhiwei He
    单位:广东医科大学附属东莞第一医院
    期刊: Frontiers in oncology
    DOI: 10.3389/fonc.2023.1104262
    Synergetic HepG2 cells suppression efficacy of Tripterygium wilfordii and Scutellaria barbata through EGFR/PI3K/Akt pathway(2022-09-01)
    IF: 3.27
    作者:Susu Liu ,Yuan Liu,Luanying He,Fei He,Na Wang,Jinting Peng...
    单位:北京化工大学
    期刊: Pharmacological Research - Modern Chinese Medicine
    DOI: 10.1016/j.prmcm.2022.100130
    Pyroptosis-Related Risk Signature Exhibits Distinct Prognostic, Immune, and Therapeutic Landscapes in Hepatocellular Carcinoma(2022-03-09)
    IF: 2.80
    作者:Yidi Zhao Qingya Song Fangshi Xu Yang Zhou Xiaoli Zuo Zhengliang Zhang
    单位:西安交通大学第二附属医院
    期刊: Frontiers in genetics
    DOI: 10.3389/fgene.2022.823443