• 商品货号：F110857

• accession：NM_018571
• 基因别名：STRADB
• 基因描述：Homo sapiens STE20-related kinase adaptor beta (STRADB), transcript variant 1, mRNA.
• 载体： 现货载体
• CDS区长度：1257
• 翻译后氨基酸长度：418
• TranscriptVariant：This variant (1) encodes the longer isoform (1).
• 基因简介：This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
• 载体信息：自有图片地址
• 规格：10ul 质粒

CDS区参考序列： 点击查看序列

ATGTCTCTTTTGGATTGCTTCTGCACTTCAAGAACACAAGTTGAATCACTCAGACCTGAAAAACAGTCTGAAACCAGTATCCATCAATACTTGGTTGATGAGCCAACCCTTTCCTGGTCACGTCCATCCACTAGAGCCAGTGAAGTACTATGTTCCACCAACGTTTCTCACTATGAGCTCCAAGTAGAAATAGGAAGAGGATTTGACAACTTGACTTCTGTCCATCTTGCACGGCATACTCCCACAGGAACACTGGTAACTATAAAAATTACAAATCTGGAAAACTGCAATGAAGAACGCCTGAAAGCTTTACAGAAAGCCGTGATTCTATCCCACTTTTTCCGGCATCCCAATATTACAACTTATTGGACAGTTTTCACTGTTGGCAGCTGGCTTTGGGTTATTTCTCCATTTATGGCCTATGGTTCAGCAAGTCAACTCTTGAGGACCTATTTTCCTGAAGGAATGAGTGAAACTTTAATAAGAAACATTCTCTTTGGAGCCGTGAGAGGGTTGAACTATCTGCACCAAAATGGCTGTATTCACAGGAGTATTAAAGCCAGCCATATCCTCATTTCTGGTGATGGCCTAGTGACCCTCTCTGGCCTGTCCCATCTGCATAGTTTGGTTAAGCATGGACAGAGGCATAGGGCTGTGTATGATTTCCCACAGTTCAGCACATCAGTGCAGCCGTGGCTGAGTCCAGAACTACTGAGACAGGATTTACATGGGTATAATGTGAAGTCAGATATTTACAGTGTTGGGATTACAGCATGTGAATTAGCCAGTGGGCAGGTGCCTTTCCAGGACATGCATAGAACTCAGATGCTGTTACAGAAACTGAAAGGTCCTCCTTATAGCCCATTGGATATCAGTATTTTCCCTCAATCAGAATCCAGAATGAAAAATTCCCAGTCAGGTGTAGACTCTGGGATTGGAGAAAGTGTGCTTGTCTCCAGTGGAACTCACACAGTAAATAGTGACCGATTACACACACCATCCTCAAAAACTTTCTCTCCTGCCTTCTTTAGCTTGGTACAGCTCTGTTTGCAACAAGATCCTGAGAAAAGGCCATCAGCAAGCAGTTTATTGTCCCATGTTTTCTTCAAACAGATGAAAGAAGAAAGCCAGGATTCAATACTTTCACTGTTGCCTCCTGCTTATAACAAGCCATCAATATCATTGCCTCCAGTGTTACCTTGGACTGAGCCAGAATGTGATTTTCCTGATGAAAAAGACTCATACTGGGAATTCTAG

翻译后氨基酸参数序列： 点击查看序列

ATGTCTCTTTTGGATTGCTTCTGCACTTCAAGAACACAAGTTGAATCACTCAGACCTGAAAAACAGTCTGAAACCAGTATCCATCAATACTTGGTTGATGAGCCAACCCTTTCCTGGTCACGTCCATCCACTAGAGCCAGTGAAGTACTATGTTCCACCAACGTTTCTCACTATGAGCTCCAAGTAGAAATAGGAAGAGGATTTGACAACTTGACTTCTGTCCATCTTGCACGGCATACTCCCACAGGAACACTGGTAACTATAAAAATTACAAATCTGGAAAACTGCAATGAAGAACGCCTGAAAGCTTTACAGAAAGCCGTGATTCTATCCCACTTTTTCCGGCATCCCAATATTACAACTTATTGGACAGTTTTCACTGTTGGCAGCTGGCTTTGGGTTATTTCTCCATTTATGGCCTATGGTTCAGCAAGTCAACTCTTGAGGACCTATTTTCCTGAAGGAATGAGTGAAACTTTAATAAGAAACATTCTCTTTGGAGCCGTGAGAGGGTTGAACTATCTGCACCAAAATGGCTGTATTCACAGGAGTATTAAAGCCAGCCATATCCTCATTTCTGGTGATGGCCTAGTGACCCTCTCTGGCCTGTCCCATCTGCATAGTTTGGTTAAGCATGGACAGAGGCATAGGGCTGTGTATGATTTCCCACAGTTCAGCACATCAGTGCAGCCGTGGCTGAGTCCAGAACTACTGAGACAGGATTTACATGGGTATAATGTGAAGTCAGATATTTACAGTGTTGGGATTACAGCATGTGAATTAGCCAGTGGGCAGGTGCCTTTCCAGGACATGCATAGAACTCAGATGCTGTTACAGAAACTGAAAGGTCCTCCTTATAGCCCATTGGATATCAGTATTTTCCCTCAATCAGAATCCAGAATGAAAAATTCCCAGTCAGGTGTAGACTCTGGGATTGGAGAAAGTGTGCTTGTCTCCAGTGGAACTCACACAGTAAATAGTGACCGATTACACACACCATCCTCAAAAACTTTCTCTCCTGCCTTCTTTAGCTTGGTACAGCTCTGTTTGCAACAAGATCCTGAGAAAAGGCCATCAGCAAGCAGTTTATTGTCCCATGTTTTCTTCAAACAGATGAAAGAAGAAAGCCAGGATTCAATACTTTCACTGTTGCCTCCTGCTTATAACAAGCCATCAATATCATTGCCTCCAGTGTTACCTTGGACTGAGCCAGAATGTGATTTTCCTGATGAAAAAGACTCATACTGGGAATTCTAG