- 商品货号:F110855
- accession:NM_004041
- 基因别名:ARRB1
- 基因描述:Homo sapiens arrestin, beta 1 (ARRB1), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1257
- 翻译后氨基酸长度:418
- TranscriptVariant:This variant (1) represents the longer transcript variant and encodes the longer isoform (A).
- 基因简介:Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列