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- accession：NM_008010
- 基因别名：Fgfr3
- 基因描述：Mus musculus fibroblast growth factor receptor 3 (Fgfr3), transcript variant 1, mRNA.
- 载体：现货载体
- CDS区长度：2403
- 翻译后氨基酸长度：800
- TranscriptVariant：This variant (1) encodes isoform 1, also known as IIIc, which includes the IIIc-type C-terminal half of the IgIII domain. Variants 1 and 2 encode the same protein.
- 基因简介：This gene encodes a member of the fibroblast growth factor receptor family. Members of this family are highly conserved proteins that differ from one another in their ligand affinities and tissue distribution. A representative protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene may be associated with craniosynostosis and multiple types of skeletal dysplasia. A pseudogene of this gene is located on chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
