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- accession：NM_001163217
- 基因别名：Fgfr3
- 基因描述：Mus musculus fibroblast growth factor receptor 3 (Fgfr3), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：2409
- 翻译后氨基酸长度：802
- TranscriptVariant：This variant (4) lacks a coding exon and includes an alternate exon in the coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (3, also known as IIIb) is longer than isoform 1 and includes the IIIb-type C-terminal half of the IgIII domain. The combination of alternative exons and splice sites in the coding region is inferred based on human NM_001163213.1.
- 基因简介：This gene encodes a member of the fibroblast growth factor receptor family. Members of this family are highly conserved proteins that differ from one another in their ligand affinities and tissue distribution. A representative protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene may be associated with craniosynostosis and multiple types of skeletal dysplasia. A pseudogene of this gene is located on chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
