- accession:NM_001166018
- 基因别名:POU6F2
- 基因描述:Homo sapiens POU class 6 homeobox 2 (POU6F2), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:1968
- 翻译后氨基酸长度:655
- TranscriptVariant:This variant (2) lacks an in-frame segment in the 3' coding region, as compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
- 基因简介:This gene encodes a member of the POU protein family characterized by the presence of a bipartite DNA binding domain, consisting of a POU-specific domain and a homeodomain, separated by a variable polylinker. The DNA binding domain may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner. The POU family members are transcriptional regulators, many of which are known to control cell type-specific differentiation pathways. This gene is a tumor suppressor involved in Wilms tumor (WT) predisposition. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
- 规格:10ul 质粒
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