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人 SCN11A (NM_001287223) cDNA克隆
人 SCN11A (NM_001287223) cDNA克隆
  • 商品货号:FC129911
  • 已售 4 件 | 评价 0 人次 | 关注度 336
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    • accession:NM_001287223
    • 基因别名:SCN11A
    • 基因描述:Homo sapiens sodium channel, voltage-gated, type XI, alpha subunit (SCN11A), transcript variant 2, mRNA.
    • 载体:现货载体
    • CDS区长度:5376
    • 翻译后氨基酸长度:1791
    • TranscriptVariant:This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
    • 基因简介:Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in the rising phase of the action potential in most excitable cells. Alpha subunits, such as SCN11A, mediate voltage-dependent gating and conductance, while auxiliary beta subunits regulate the kinetic properties of the channel and facilitate membrane localization of the complex. Aberrant expression patterns or mutations of alpha subunits underlie a number of disorders. Each alpha subunit consists of 4 domains connected by 3 intracellular loops; each domain consists of 6 transmembrane segments and intra- and extracellular linkers.[supplied by OMIM, Apr 2004]
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列