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- accession：NM_022377
- 基因别名：ICAM4
- 基因描述：Homo sapiens intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 2, mRNA.
- 载体：现货载体
- CDS区长度：714
- 翻译后氨基酸长度：237
- TranscriptVariant：This variant (2) includes the intronic sequence between exons 2 and 3, which results in a frameshift and early translation termination, compared to variant 1. The encoded isoform (2) thus has the same N-terminus, but has a truncated C-terminus that lacks the transmembrane and cytoplasmic domains, compared to isoform 1.
- 基因简介：This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
