- accession:NM_001544
- 基因别名:ICAM4
- 基因描述:Homo sapiens intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) (ICAM4), transcript variant 1, mRNA.
- 载体:现货载体
- CDS区长度:816
- 翻译后氨基酸长度:271
- TranscriptVariant:This variant (1) encodes the full-length isoform (1) that contains 2 Ig-like C2-type domains, a single transmembrane domain, and a single cytoplasmic domain.
- 基因简介:This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
- 规格:10ul 质粒
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