• 靶点-Target： MKK3/6
• MW(Observed)： 40kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:1000
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant human MKK6 protein fragments expressed in E.coli.
• 特异性： This antibody detects endogenous levels of MKK3 and MKK6 and does not cross-react with related proteins.
• 基因名称： map2k3
• Organism-1： Human
• 基因ID-1： 5608
• SwissProt-1： P52564
• Organism-2： Mouse
• SwissProt-2： P70236
• 背景： This gene encodes a member of the dual specificity protein kinase family， which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases， also known as extracellular signal-regulated kinases (ERKs)， act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway， this gene is involved in many cellular processes such as stress induced cell cycle arrest， transcription activation and apoptosis. [provided by RefSeq， Jul 2008]，
• 细胞定位： Nucleus . Cytoplasm . Cytoplasm， cytoskeleton . Binds to microtubules.

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