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- 靶点-Target: RBBP5
- MW(Observed): 70kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:1000;ICC 1:100;IF 1:50-200
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant human RBBP5 protein fragments expressed in E.coli.
- 特异性: This antibody detects endogenous levels of RBBP5 and does not cross-react with related proteins.
- 基因名称: rbbp5
- Organism-1: Human
- 基因ID-1: 5929
- SwissProt-1: Q15291
- Organism-2: Mouse
- SwissProt-2: Q8BX09
- 背景: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010],
- 细胞定位: Nucleus .