• 靶点-Target： ATIC
• MW(Observed)： 64kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:1000
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant human ATIC protein fragments expressed in E.coli.
• 特异性： This antibody detects endogenous levels of ATIC and does not cross-react with related proteins.
• 基因名称： atic
• Organism-1： Human
• 基因ID-1： 471
• SwissProt-1： P31939
• Organism-2： Mouse
• SwissProt-2： Q9CWJ9
• 背景： This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity， and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq， Sep 2009]，
• 细胞定位： mitochondrion，cytosol，cell-cell adherens junction，membrane，extracellular exosome，

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