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- 靶点-Target: TCP-1 β
- MW(Calculated): 57kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-1:2000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: Affinity purification
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant fragment of human TCP-1 β expressed in E. Coli.
- 特异性: TCP-1 β Monoclonal Antibody detects endogenous levels of TCP-1 β protein.
- 基因名称: CCT2
- 蛋白名称: T-complex protein 1 subunit beta
- Organism-1: Human
- 基因ID-1: 10576
- SwissProt-1: P78371
- Organism-2: Mouse
- 基因ID-2: 12461
- SwissProt-2: P80314
- Organism-3: Rat
- 基因ID-3: 299809
- SwissProt-3: Q5XIM9
- 背景: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010],
- 细胞定位: Cytoplasm .