资料下载
- 靶点-Target: MTHFR
- MW(Calculated): 75kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-1:2000;IHC 1:200-1:1000;ELISA 1:10000;IF 1:50-200
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: Affinity purification
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant fragment of human MTHFR expressed in E. Coli.
- 特异性: MTHFR Monoclonal Antibody detects endogenous levels of MTHFR protein.
- 基因名称: MTHFR
- 蛋白名称: Methylenetetrahydrofolate reductase
- Organism-1: Human
- 基因ID-1: 4524
- SwissProt-1: P42898
- Organism-2: Mouse
- SwissProt-2: Q9WU20
- 背景: The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009],
- 细胞定位: cytosol,synapse,