• 靶点-Target： HSP90B
• MW(Calculated)： 83kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： Affinity purification
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant fragment of human HSP90β expressed in E. Coli.
• 特异性： HSP90β Monoclonal Antibody detects endogenous levels of HSP90β protein.
• 基因名称： HSP90AB1
• 蛋白名称： Heat shock protein HSP 90-beta
• Organism-1： Human
• 基因ID-1： 3326
• SwissProt-1： P08238
• Organism-2： Mouse
• 基因ID-2： 15516
• SwissProt-2： P11499
• Organism-3： Rat
• 基因ID-3： 301252
• SwissProt-3： P34058
• 背景： This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction， protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes. [provided by RefSeq， Dec 2012]，
• 细胞定位： Cytoplasm . Melanosome . Nucleus . Secreted . Cell membrane . Dynein axonemal particle . Cell surface . Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). Translocates with BIRC2 from the nucleus to the cytoplasm during differentiation (PubMed:18239673). Secreted when associated with TGFB1 processed form (LAP) (PubMed:20599762). .

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