• 靶点-Target： HSP27
• MW(Calculated)： 23kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;Flow Cyt 1:200-1:400;ELISA 1:10000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： Affinity purification
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant fragment of human HSP27 expressed in E. Coli.
• 特异性： HSP27 Monoclonal Antibody detects endogenous levels of HSP27 protein.
• 基因名称： HSPB1
• 蛋白名称： Heat shock protein beta-1
• Organism-1： Human
• 基因ID-1： 3315
• SwissProt-1： P04792
• Organism-2： Mouse
• SwissProt-2： P14602
• Organism-3： Rat
• 基因ID-3： 24471
• SwissProt-3： P42930
• 背景： The protein encoded by this gene is induced by environmental stress and developmental changes. The encoded protein is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in this gene are a cause of Charcot-Marie-Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN). [provided by RefSeq， Oct 2008]，
• 细胞定位： Cytoplasm . Nucleus . Cytoplasm， cytoskeleton， spindle . Cytoplasmic in interphase cells. Colocalizes with mitotic spindles in mitotic cells. Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles. .

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