• 靶点-Target： GRK 2
• MW(Calculated)： 80kD
• 宿主物种-Host Species： Mouse
• 修饰-Modification： Unmodified
• 推荐稀释比： WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
• 组成： Liquid in PBS containing 50% glycerol， 0.5% BSA and 0.02% sodium azide.
• 纯化工艺： Affinity purification
• 储存： -15°C to -25°C/1 year(Do not lower than -25°C)
• 克隆性： Monoclonal
• 免疫原： Purified recombinant fragment of human GRK 2 expressed in E. Coli.
• 特异性： GRK 2 Monoclonal Antibody detects endogenous levels of GRK 2 protein.
• 基因名称： ADRBK1
• 蛋白名称： Beta-adrenergic receptor kinase 1
• Organism-1： Human
• 基因ID-1： 156
• SwissProt-1： P25098
• Organism-2： Mouse
• SwissProt-2： Q99MK8
• Organism-3： Rat
• 基因ID-3： 25238
• SwissProt-3： P26817
• 背景： The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq， Jul 2008]，
• 细胞定位： Cytoplasm . Cell membrane . Cell junction， synapse， postsynapse . Cell junction， synapse， presynapse .

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