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- 靶点-Target: AATM
- MW(Calculated): 48kD
- 宿主物种-Host Species: Mouse
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-1:2000;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: Affinity purification
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 克隆性: Monoclonal
- 免疫原: Purified recombinant fragment of human AATM expressed in E. Coli.
- 特异性: AATM Monoclonal Antibody detects endogenous levels of AATM protein.
- 基因名称: GOT2
- 蛋白名称: Aspartate aminotransferase, mitochondrial
- Organism-1: Human
- 基因ID-1: 2806
- SwissProt-1: P00505
- Organism-2: Mouse
- 基因ID-2: 14719
- SwissProt-2: P05202
- Organism-3: Rat
- 基因ID-3: 25721
- SwissProt-3: P00507
- 背景: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013],
- 细胞定位: Mitochondrion matrix . Cell membrane . Exposure to alcohol promotes translocation to the cell membrane. .