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- 靶点-Target: SUMO-2/3
- MW(Observed): 11kD
- 宿主物种-Host Species: Rabbit
- 同种型-Isotype: IgG
- 修饰-Modification: Unmodified
- 推荐稀释比: WB 1:500-1:2000;ELISA 1:20000;IP 1:50-100;Not yet tested in other applications.
- 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
- 浓度: 1 mg/ml
- 克隆性: Polyclonal
- 免疫原: The antiserum was produced against synthesized peptide derived from human SUMO2/3. AA range:44-93
- 特异性: Cleaved-SUMO-2/3 (G93) Polyclonal Antibody detects endogenous levels of fragment of activated SUMO-2/3 protein resulting from cleavage adjacent to G93.
- 基因名称: SUMO2 SUMO3
- 蛋白名称: Small ubiquitin-related modifier 2
- Organism-1: Human
- 基因ID-1: 6613
- SwissProt-1: P61956;P55854
- Organism-2: Mouse
- 基因ID-2: 170930
- SwissProt-2: P61957
- Organism-3: Rat
- 基因ID-3: 690244
- SwissProt-3: P61959
- 背景: This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
- 细胞定位: Nucleus. Nucleus, PML body.