- accession:NM_029702
- 基因别名:AI480700; 1500006I01Rik
- 基因描述:Mus musculus ADP-ribosylation factor related protein 1 (Arfrp1), transcript variant 2, mRNA.
- 载体:现货载体
- CDS区长度:606
- 翻译后氨基酸长度:201
- TranscriptVariant:This variant (2) uses an alternate splice site in the 5' UTR compared to variant 1. Variants 1, 2 and 3 encode the same isoform (1).
- 基因简介:The gene encodes a membrane-associated GTPase that is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. It plays an essential role in Golgi function controlling recruitment of GRIP domain proteins and ARL1 to the trans-Golgi and trans-Golgi to plasma membrane trafficking of cell surface proteins such as E-cadherin. Deletion of this gene in mice leads to embryonic lethality during early gastrulation, which is at least partly caused by the disruption of E-cadherin trafficking to the cell surface and therefore lack of sufficient cell-cell adhesion in the embryo. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- 规格:10ul 质粒
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