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- accession：NM_001165995
- 基因别名：AI480700; 1500006I01Rik
- 基因描述：Mus musculus ADP-ribosylation factor related protein 1 (Arfrp1), transcript variant 4, mRNA.
- 载体：现货载体
- CDS区长度：465
- 翻译后氨基酸长度：154
- TranscriptVariant：This variant (4) lacks an alternate exon in the 5' region that results in a distinct 5' UTR and causes translation initiation at a downstream start codon, compared to variant 1. The encoded protein (isoform 2) has a shorter N-terminus, compared to isoform 1.
- 基因简介：The gene encodes a membrane-associated GTPase that is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) genes. It plays an essential role in Golgi function controlling recruitment of GRIP domain proteins and ARL1 to the trans-Golgi and trans-Golgi to plasma membrane trafficking of cell surface proteins such as E-cadherin. Deletion of this gene in mice leads to embryonic lethality during early gastrulation, which is at least partly caused by the disruption of E-cadherin trafficking to the cell surface and therefore lack of sufficient cell-cell adhesion in the embryo. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
- 规格：10ul 质粒
CDS区参考序列： 点击查看序列翻译后氨基酸参数序列： 点击查看序列
