- accession:NM_013358
- 基因别名:PADI1
- 基因描述:Homo sapiens peptidyl arginine deiminase, type I (PADI1), mRNA.
- 载体: 现货载体
- CDS区长度:1992
- 翻译后氨基酸长度:663
- 基因简介:This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type I enzyme is involved in the late stages of epidermal differentiation, where it deiminates filaggrin and keratin K1, which maintains hydration of the stratum corneum, and hence the cutaneous barrier function. This enzyme may also play a role in hair follicle formation. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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