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人SUN2(NM_015374)ORF克隆
人SUN2(NM_015374)ORF克隆
  • 商品货号:FO124918
  • 已售 3 件 | 评价 0 人次 | 关注度 415
    • accession:NM_015374
    • 基因别名:SUN2
    • 基因描述:Homo sapiens Sad1 and UNC84 domain containing 2 (SUN2), transcript variant 2, mRNA.
    • 载体: 现货载体
    • CDS区长度:2154
    • 翻译后氨基酸长度:717
    • TranscriptVariant:This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
    • 基因简介:SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
    • 载体信息:自有图片地址
    • 规格:10ul 质粒
    CDS区参考序列: 点击查看序列
    翻译后氨基酸参数序列: 点击查看序列