- 商品货号:A16833
- 名称:PK11007
- 简介:PK11007 is an anti-p53 drug that stabilizes wild type and mutant p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. It exerts antitumor functions not only via reactivating p53 but also via other cellular mechanisms, such as increase of cellular ROS to toxic levels and activation of the UPR.
- CASNO:38275-34-2
- 分子式:C6H5ClN2O4S
- 分子量:236.63
- SMILES:CS(=O)(=O)C1=NC=C(C(=N1)C(=O)O)Cl
- 保持条件:at -20°C 3 years Powder
- 同名:PK 11007, PK-11007
- 纯度:>98%
- 应用:p53 activator