- 商品货号:A15487
- 名称:UNC0642
- 简介:UNC0642 is a potent and selective G9a and GLP histone lysine methyltransferase inhibitor (IC50 < 2.5 nM). It reduces H3K9 dimethylation levels in MDA-MB-231 cells (IC50 = 110 nM). Displays modest brain penetration in vivo.
- CASNO:1481677-78-4
- 分子式:C29H44F2N6O2
- 分子量:546.69
- SMILES:CC(C)N1CCC(CC1)NC2=NC(=NC3=CC(=C(C=C32)OC)OCCCN4CCCC4)N5CCC(CC5)(F)F
- 保持条件:at -20°C 3 years Powder
- 同名:UNC 0642, UNC-0642
- 纯度:>98%
- 应用:G9a/GLP inhibitor
- 作用机制:Inhibitor