• 名称：KRX-0402
• 简介：KRX-0402 is a small molecule that was specifically designed to block the DNA repair protein, MGMT. MGMT confers resistance to certain alkylating agents, such as temozolomide and BCNU, that are commonly used to treat brain cancer, melanoma and non-Hodgkin’s lymphoma.
• CASNO：1000874-21-4
• 分子式：C12H11N5O
• 分子量：241.25
• SMILES：NC1=NC(OCC2=CC=CC=C2)=C3NC=NC3=N1
• 保持条件：at -20°C 3 years Powder
• 同名：O6-benzyl guanine, O6-BG
• 纯度：>98%
• 应用：DNA repair inhibitor
• 作用机制：Inhibitor