- accession:NM_006984
- 基因别名:CLDN10
- 基因描述:Homo sapiens claudin 10 (CLDN10), transcript variant b, mRNA.
- 载体: 现货载体
- CDS区长度:687
- 翻译后氨基酸长度:228
- TranscriptVariant:This variant (b) differs in the 5' UTR and 5' coding region, representing use of an alternate promoter, compared to variant a. The resulting isoform (b) has a longer and distinct N-terminus, compared to isoform a.
- 基因简介:This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.[provided by RefSeq, Jun 2010]
- 载体信息:自有图片地址
- 规格:10ul 质粒
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