- 名称:Netupitant
- 简介:Netupitant is a selective neurokinin 1 (NK1) receptor antagonist. It competitively binds to and blocks the activity of the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV).
- CASNO:290297-26-6
- 分子式:C30H32F6N4O
- 分子量:578.59
- SMILES:CC1=CC=CC=C1C2=CC(=NC=C2N(C)C(=O)C(C)(C)C3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)N4CCN(CC4)C
- 保持条件:at -20°C 3 years Powder
- 同名:D05152, AG-E-94200
- 纯度:>98%
- 应用:NK1 receptor antagonist
- 作用机制:Antagonist