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3-deazaneplanocin A HCl (DZNep HCl)
3-deazaneplanocin A HCl (DZNep HCl)
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  • 商品货号:A13947
  • 名称:3-deazaneplanocin A HCl (DZNep HCl)
  • 简介:3-deazaneplanocin A, also known as DZNep, is a well-known histone methyltransferase inhibitor, which disrupts polycomb-repressive complex 2 (PRC2), and induces apoptosis, while inhibiting proliferation and metastasis, in cancer cells, including acute myeloid leukemia, breast cancer and glioblastoma.
  • CASNO:120964-45-6
  • 分子式:C12H15ClN4O3
  • 分子量:298.73
  • SMILES:C1=CN=C(C2=C1N(C=N2)[C@@H]3C=C([C@H]([C@H]3O)O)CO)N.Cl
  • 保持条件:at -20°C 3 years Powder
  • 同名:DZNep, NSC 617989
  • 纯度:>98%
  • 应用:EZH2 inhibitor
  • 作用机制:Inhibitor