- 名称:GNF 5837
- 简介:GNF-5837 is a potent, selective, and orally bioavailable pan-TRK inhibitor that inhibited tumor growth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF.
- CASNO:1033769-28-6
- 分子式:C28H21F4N5O2
- 分子量:535.49
- SMILES:CC1=C(C=C(C=C1)NC(=O)NC2=C(C=CC(=C2)C(F)(F)F)F)NC3=CC4=C(C=C3)/C(=C/C5=CC=CN5)/C(=O)N4
- 保持条件:at -20°C 3 years Powder
- 同名:GNF-5837, GNF5837
- 纯度:>98%
- 应用:TRK inhibitor
- 作用机制:Inhibitor