• 名称：ZCL-278
• 简介：ZCL-278 is a selective inhibitor of Cdc42. Targets the binding site of the Cdc42 guanine nucleotide exchange factor, intersectin (ITSN). Inhibits Cdc42-mediated cellular effects, including microspike formation in 3T3 fibroblasts and neuronal branching in primary neonatal cortical neurons. Also suppresses cell motility and migration in PC3 cells, without cytotoxic effects.
• CASNO：587841-73-4
• 分子式：C21H19BrClN5O4S2
• 分子量：584.89
• SMILES：CC1=CC(=NC(=N1)NS(=O)(=O)C2=CC=C(C=C2)NC(=S)NC(=O)COC3=C(C=C(C=C3)Br)Cl)C
• 保持条件：at -20°C 3 years Powder
• 同名：ZCL278, ZCL 278
• 纯度：>98%
• 应用：Cdc42 GTPase inhibitor
• 作用机制：Inhibitor