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XL-228
XL-228
会员等级价V
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  • 商品货号:A13069
  • 名称:XL-228
  • 简介:XL228 is a protein kinase inhibitor targeting IGF1R, the AURORA kinases, FGFR1-3, ABL and SRC family kinases. XL228 is an Aurora A inhibitor (IC50, f3 nmol/L) that has shown potent biochemical activity against ABL1 (Ki, 5 nmol/L), as well as the BCR-ABL1 T315I (Ki, 1.4 nmol/L) kinases.
  • CASNO:898280-07-4
  • 分子式:C28H37N9O
  • 分子量:515.65
  • SMILES:CC(C)C1=NOC(=C1)CNC2=NC(=CC(=N2)NC3=NNC(=C3)C4CC4)N5CCN(CC5)C
  • 保持条件:at -20°C 3 years Powder
  • 纯度:>98%
  • 应用:IGF-1R, Aurora, FGFR, ABL, SRC inhibitor
  • 作用机制:Inhibitor