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Letaxaban (TAK-442)
Letaxaban (TAK-442)
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  • 商品货号:A12871
  • 名称:Letaxaban (TAK-442)
  • 简介:Letaxaban, also known as TAK-442, is a potent, selective, and orally active factor Xa inhibitor, which is a tetrahydropyrimidin-2(1H)-one derivative. TAK-442 inhibited endogenous FXa activity in platelet-poor human [half-maximal inhibitory concentration (IC(50)): 53 nM, TAK-442] and rat (IC(50): 32 nM, TAK-442) plasma.
  • CASNO:870262-90-1
  • 分子式:C22H26ClN3O5S
  • 分子量:479.98
  • SMILES:C1CNC(=O)N(C1)C2CCN(CC2)C(=O)[C@@H](CS(=O)(=O)C3=CC4=C(C=C3)C=C(C=C4)Cl)O
  • 保持条件:at -20°C 3 years Powder
  • 同名:TAK 442; TAK442
  • 纯度:>98%
  • 应用:factor Xa inhibitor
  • 作用机制:Inhibitor