- accession:NM_001558
- 基因别名:IL10RA
- 基因描述:Homo sapiens interleukin 10 receptor, alpha (IL10RA), transcript variant 1, mRNA.
- 载体: 现货载体
- CDS区长度:1737
- 翻译后氨基酸长度:578
- TranscriptVariant:This variant (1) is the protein-coding transcript.
- 基因简介:The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
- 载体信息:自有图片地址
- 规格:10ul 质粒
CDS区参考序列: 点击查看序列翻译后氨基酸参数序列: 点击查看序列