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Apalutamide (ARN-509)
Apalutamide (ARN-509)
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  • 商品货号:A11923
  • 名称:Apalutamide (ARN-509)
  • 简介:ARN-509 is an androgen receptor antagonist with potential antineoplastic activity. ARN-509 binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR-responsive genes.
  • CASNO:956104-40-8
  • 分子式:C21H15F4N5O2S
  • 分子量:477.4
  • SMILES:CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CN=C(C(=C4)C(F)(F)F)C#N)F
  • 保持条件:at -20°C 3 years Powder
  • 同名:ARN509
  • 纯度:>98%
  • 应用:Androgen Receptor inhibitor
  • 作用机制:Inhibitor