• 名称：Apalutamide (ARN-509)
• 简介：ARN-509 is an androgen receptor antagonist with potential antineoplastic activity. ARN-509 binds to AR in target tissues thereby preventing androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot be translocated to the nucleus. This prevents binding to and transcription of AR-responsive genes.
• CASNO：956104-40-8
• 分子式：C21H15F4N5O2S
• 分子量：477.4
• SMILES：CNC(=O)C1=C(C=C(C=C1)N2C(=S)N(C(=O)C23CCC3)C4=CN=C(C(=C4)C(F)(F)F)C#N)F
• 保持条件：at -20°C 3 years Powder
• 同名：ARN509
• 纯度：>98%
• 应用：Androgen Receptor inhibitor
• 作用机制：Inhibitor