- 名称:Nutlin 3a
- 简介:Nutlin 3a is a potent inhibitor of MDM2 (mouse double minute 2) binding to p53 that induces the expression of p53 regulated genes, and shows potent antiproliferative activity in cells expressing functional p53.
- CASNO:675576-98-4
- 分子式:C30H30Cl2N4O4
- 分子量:581.49
- SMILES:CC(C)OC1=C(C=CC(=C1)OC)C2=N[C@H]([C@H](N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl
- 保持条件:at -20°C 3 years Powder
- 同名:Nutlin-3a, (-)-Nutlin-3
- 纯度:>98%
- 应用:MDM2 inhibitor
- 作用机制:Inhibitor